Promising Possible Universal Cancer Treatment

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Two years ago, Nextbigfuture highlighted Maia Biotechnology, which might have the most promising treatment for all cancers. They poison cells that express the telomerase enzyme which indicates cancerous activity. The drug treatment is called Thio. 90% of cancers express telomerase enzyme.

Brian Wang interviewed Antiaging expert Aubrey de Grey. Aubrey told Nextbigfuture that his favorite company and approach for a broadly applicable treatment for cancer is at Maia Biotechnology.

He calls THIO “by far the most promising universal anti-cancer drug ever brought to the market”

Maia is using a telomere approach. THIO is a potentially first-in-class small molecule that is the only direct telomere targeting agent currently in clinical development. Telomerase is present in over 85% of human cancers and contributes significantly to the proliferation and reproductive immortality of cancer cells. THIO’s in vitro activity has been studied in models of several tumor types with active telomerase.

Here is the latest investor information from MAIA.

8 thoughts on “Promising Possible Universal Cancer Treatment”

  1. Like so many proclaimed breakthroughs, in medicine or nuclear fusion, I’ll wait for reproducible, unambiguous results. Of course, I’m hopeful. Historic events in medicine and in other sciences often happen with unorthodox, but at the same time very RATIONAL, scientific approach’s. For example, some may think treating cancer lies in developing a “better” chemo cocktail. A better chemical weapon that attacks a lot more then just the cancer. Perhaps this group has found a better approach. I’ll be watching, w/hope.

    Another area were innovation is needed is antibiotics. Evolution happens, and sometimes kills us when bacteria adapt to our antibiotics. This is a major medical problem. An unfortunate aside, is antibiotics once invented are cheap to make, but have never been “big money makers”. Certain cancer drugs, and other exotic (and not so exotic) drugs can cost as much to keep you alive for a year, as an “average” house, (even in todays market). This is insane, but I digress.

    Perhaps it’s time to look at the post-antibiotic era. New antibiotics will sooner or later fail against evolution. Bacteria have to us, very short lifespans, so they evolve very quickly. New research into bacterial phages which are virus’s that attack specific bacteria may address several problems. I won’t rule out bacteria could not develop immunity to a initially lethal virus. (Hell, that’s why vaccines work) But it could put multiple obstacles to adaptation. And if we make those obstacles adapt as well?

    Antibiotics also kill good bacteria essential for our digestion, immune system, and possibly neurological health. We need to do better. We adapt fastest, by learning and trying new things. Systemically.

  3. Does that mean we could in the future use more aggressive partial reprogramming without the fear of cancer ?

  4. The big IF is what other cells besides the cancer cells, will be killed.
    Telomerase is expressed a lot…

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